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Rx Deramaxx Chewable Tablets - Jeffers - Animal Health & Wellness > Medicine

Rx Deramaxx (deracoxib) Chewable Tablets for Dogs

by Deramaxx
SKU 012NOV08-100-30
$110.08
$1.83 - $316.52
$110.08
$110.08
$1.83 - $316.52
$110.08
Availability:
Out of stock
Availability:
Only 2 left!
Availability:
Only 2 left!
Availability:
Out of stock
Availability:
Out of stock
Availability:
Only 1 left!
Availability:
5+ in stock, ready to be shipped
Availability:
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Availability:
Out of stock
Dosage: 100 mg
Count: 30 tablets
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Prescription Item

Requires Veterinarian Authorization. We'll collect your pet's prescription information at Checkout.

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Rx Deramaxx for Dogs

Deramaxx for dogs (deracoxib) is a non-narcotic, non-steroidal anti-inflammatory drug of the coxib class that controls pain and inflammation associated with chronic osteoarthritis. DERAMAXX tablets are round, biconvex, chewable tablets that contain deracoxib formulated with beefy flavoring. The molecular weight of deracoxib is 397.38. The empirical formula is C17-H14-F3-N3-O3-S. Deracoxib is 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazole-1-yl] benzenesulfonamide, and can be termed a diaryl substituted pyrazole.

Non-linear elimination kinetics are exhibited at doses above 8 mg/kg/day, at which competitive inhibition of constitutive COX-1 may occur. Deracoxib is not excreted as parent drug in the urine. The major route of elimination of deracoxib is by hepatic biotransformation producing four major metabolites, two of which are characterized as products of oxidation and o-demethylation. The majority of deracoxib is excreted in feces as parent drug or metabolite. Large intersubject variability was observed in drug metabolite profiles of urine and feces. No statistically significant differences between genders were observed.

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